Insulin AND leptin drop is mandatory to initiate fat burning in weight loss (rat study)

https://www.diabetes.co.uk/news/2018/jan/drop-in-both-insulin-and-leptin-needed-for-fat-burning-to-occur-90969878.html

http://www.cell.com/cell/fulltext/S0092-8674(17)31443-5

http://www.cell.com/cms/attachment/2118937789/2086968418/fx1.jpg

http://www.cell.com/cell/fulltext/S0092-8674(12)00217-6