lundi 17 septembre 2012

A great live fermented drink: watermelon!

Best buy in Perpignan France fresh watermelon juice from locally grown fruits
First buy a fresh non pasteurized non filtered watermelon juice. Or make it!  Let it fermented spontaneously at room temperature. Then after 24 h refrigerate it and begin to drink it after 12 hours. Obviously temperature humidity and other factors play a role in fermentation so the delay may vary... Adapt to your ecosystem. More for extreme low carb dieters the drink will change with time even at 6° Celsius because the sugar content decreases, so you can keep it in your frig... Try and do your own fermentation process. 
You got a fruit kefir! 
Health benefits of watermelon? the answer is yes, at least through L-citrulline! In watermelon Kefir the amount of L-Citrulline is less than in fresh juice because bacteria use free amino acids for their metabolism. But the amount is maily dependent of the cultivar of watermelon.

 2012 Jun;25(6):640-3. doi: 10.1038/ajh.2012.20. Epub 2012 Mar 8.

Watermelon extract supplementation reduces ankle blood pressure and carotid augmentation index in obese adults with prehypertension or hypertension.

Source

Department of Nutrition, Food and Exercise Sciences, College of Human Sciences, Florida State University, Tallahassee, Florida, USA. afiguero@fsu.edu

Abstract

BACKGROUND:

Ankle-brachial index (ABI) and ankle blood pressure (BP) are associated with increased carotid wave reflection (augmentation index, AIx). Oral L-citrulline and L-arginine from synthetic or watermelon sources have reduced brachial BP, aortic BP, and aortic AIx. A directly measured carotid AIx (cAIx) rather than aortic AIx has been proposed as a better measurement of central AIx. We evaluated the effects of watermelon extract on ankle BP and cAIx in individuals with normal ABI and prehypertension or stage 1 hypertension.

METHODS:

Ankle and brachial systolic BP (SBP), diastolic BP (DBP), mean arterial pressure (MAP), cAIx, ABI, and heart rate (HR) were evaluated in the supine position in 14 adults (11 women/3 men, age 58 ± 1 years) with prehypertension or stage 1 hypertension (153 ± 4 mm Hg). Subjects were randomly assigned to 6 weeks of watermelon extract supplementation (L-citrulline/L-arginine, 6 g daily) or placebo followed by a 2-week washout period and then crossover.

RESULTS:

Ankle and brachial SBP (-11.5 ± 3.8 and -15.1 ± 2.8 mm Hg), DBP (-7.8 ± 2.3 and -7.6 ± 1.8 mm Hg), and MAP (-9.8 ± 2.6 and -7.3 ± 1.8 mm Hg), and cAIx (-8.8 ± 2.6 %) decreased significantly (P < 0.05) after watermelon supplementation compared to placebo. Watermelon supplementation had no significant effect (P > 0.05) on ABI and HR.

CONCLUSIONS:

This study shows that watermelon extract supplementation reduces ankle BP, brachial BP, and carotid wave reflection in obese middle-aged adults with prehypertension or stage 1 hypertension and normal ABI, which may reflect improved arterial function.

http://www.biotechnologyforbiofuels.com/content/pdf/1754-6834-2-18.pdf



Delicious whole fermented non pasteurized watermelon juice!  



You need Calcium? You went paleo recently?

Usually 9/10 of my friends who went paleo and even men ask the terrific question: how can I find Calcium for my bones in my new diet?
Ok I know they need protein and sun or vitamin D, but if they eat paleo they will find a lot of calcium in greens and ... Oysters! More delicious than raw parsley!

vendredi 14 septembre 2012

About the recent meta analysis on long w3 PUFA

This study is a meta analysis. Pooling results is not the mantra of valid statistiscs...


In other words they don't reject the null hypothesis by pooling the data of 30 studies which are very different...

In my point of view it's not a strong evidence. And I am more confident in RCT when I see a patient and when he fit with the criteria of a RCT.

So long chain PUFA as other supplements or drugs are to be prescribed in selective patients when strong clinical evidence is available through JELIS, GISSI ...

Nevertheless this meta analysis should be considered to design new studies R and C in selective patients and during sufficient time to look at a lowering effect on CV deaths in the present era of statin use and a higher prevalence of obesity and D2.

http://www.forbes.com/sites/larryhusten/2012/09/11/more-evidence-that-omega-3-supplements-dont-work/
http://www.practicaldiabetes.com/SpringboardWebApp/userfiles/espdi/file/DN%20Walker.pdf



vendredi 7 septembre 2012

Wine: no benefit of alcohol?

I was a few years ago invited to a conference in Pau set up by a local physician organization and the different speakers advocated wine drinking in order to decrease CV diseases.
The management of the organization and the speakers were obviously tied with Bordeaux wine lobbies. They were from Bordeaux or trained in Bordeaux.
I asked the painful question:
"Is fermented grape juice of low alcohol content or non alcoholised as efficient in reducing the CV risk?"
The speaker in an arrogant answer considered my question completely stupid.
The answer of science is there. I don't remember the name of this speaker and the history of science will do the same... on the contrary in the future we will benefit of non alcoholised fermented beverages because of high polyphenol content (including resveratrol) without the doubtful benefits of alcohol even in tiny amount.

http://circres.ahajournals.org/content/early/2012/09/06/CIRCRESAHA.112.275636.full.pdf+html