A great personal view on this issue!

The Lancet Diabetes & Endocrinology

Available online 30 August 2013

In Press, Corrected Proof — Note to users

Personal View

Metabolically healthy obesity: epidemiology, mechanisms, and clinical implications

• Prof Norbert Stefan, MD^a, b, c, 
• Prof Hans-Ulrich Häring, MD^a, b, c, 
• Prof Frank B Hu, MD^d, e, f, 
• Prof Matthias B 

Schulze, DrPH^c, g, , 

http://www.medscape.com/viewarticle/810325?

We all know that patients with obesity do not share the same cardiovascular and metabolic risks.
Some patients despite of obesity keep a good profile of biomarkers in the blood. They didn't develop insulin resistance, and they don't have accelerated atheroma.
The majority of patients with obesity have a high waist to hip ratio develop insulin resistance and type II diabetes.
In this setting they present frequently accelerated atheroma either in coronary circulation or in supra aortic trunks or peripheral arteries.
In this paper authors present their personal perspective on metabolically healthy obesity. It is clearly helpful to avoid aggressive treatment in patients concerned and to better understand the dramatic increase of non-healthy obesity.

http://www.medscape.com/viewarticle/738448

http://www.medscape.com/viewarticle/769460

http://www.neurology.org/content/79/8/755.abstract?sid=08eed9fb-a2d0-41e8-a127-c74dfbaa0f81