Potassium

http://articles.mercola.com/sites/articles/archive/2014/09/22/potassium-lowers-stroke-risk.aspx?e_cid=20140922Z2_PRNL_art_2&utm_source=prmrnl&utm_medium=email&utm_content=art2&utm_campaign=20140922Z2&et_cid=DM56501&et_rid=665555795

Effects of Hunter-Gatherer Subsistence Mode on Arterial Distensibility in Cameroonian Pygmies

1. Daniel Lemogoum, 
2. William Ngatchou, 
3. Christophe Janssen, 
4. Marc Leeman,
5. Luc Van Bortel, 
6. Pierre Boutouyrie, 
7. Jean Paul Degaute, 
8. Philippe Van de Borne

1. From the Hypertension Clinic (D.L., W.N., C.J., M.L., L.V.B., P.B., J.P.D., P.V.d.B.), Department of Cardiology, Université Libre de Bruxelles-Erasme Hospital, Brussels, Belgium. Heymans Institute of Pharmacology (L.V.B.), Gend University, Gend, Belgium. Department of Pharmacology (P.B.), Hôpital Européen Georges Pompidou, Paris, France.

1. Correspondence to Daniel Lemogoum, Hypertension Clinic, Department of Cardiology, Université Libre de Bruxelles-Erasme Hospital, 808, Lennik Rd 1070, Brussels, Belgium. E-mail Daniel.lemogoum@ereasme.ulb.ac.be

Abstract

We aimed to assess whether arterial distensibility estimated by pulse wave velocity (PWV) and augmentation index (AI) differs between Cameroon traditional pygmies (TPs) on hunter-gather subsistence mode, contemporary pygmies who migrated to semiurban area, and the Bantou farmers (BFs) sharing the same environment. For that purpose, we recorded carotid-femoral PWV (ComplioR) in age and sex carefully matched 20 TPs, 20 contemporary pygmies, and 22 BFs. Aortic AI corrected for heart rate and blood pressures were generated from pressure wave analysis (SphygmoCor). Lipid profile was determined in TP and BF participants. TPs were shorter (P=0.02) with lower body weight (P<0 .01="" and="" bfs.="" bfs="" but="" cholesterol="" comparison="" contemporary="" em="" had="" high-density="" higher="" in="" lipoprotein="" low-density="" lower="" pygmies="" style="border: 0px; font-family: inherit; font-size: inherit; font-weight: inherit; line-height: inherit; margin: 0px; outline-style: none; padding: 0px; text-align: inherit; vertical-align: baseline;" than="" tps="" with="">P

<0 .01="" em="" m="" pwv="" s="" slower="" style="border: 0px; font-family: inherit; font-size: inherit; font-weight: inherit; line-height: inherit; margin: 0px; outline-style: none; padding: 0px; text-align: inherit; vertical-align: baseline;" their="" was="">P=0.006) than that of contemporary pygmies (6.82±0.36 m/s) or BFs (6.93±0.29 m/s); however, after its adjustment for age, mean arterial pressure, and heart rate, the difference was slightly attenuated (P=0.051). PWV adjusted for weight did not differ between groups (P=0.10). In the whole study population but not in TPs taken separately, multivariate regression analysis revealed that PWV was independently associated with mean arterial pressure, age, and TP status (P<0 .001="" age="" ai="" and="" aortic="" arterial="" as="" corrected="" determinants="" em="" emerged="" for="" heart="" height="" independent="" mean="" of="" pressure="" rate="" style="border: 0px; font-family: inherit; font-size: inherit; font-weight: inherit; line-height: inherit; margin: 0px; outline-style: none; padding: 0px; text-align: inherit; vertical-align: baseline;" whereas="">P<0 .001="" 3="" aging="" ai="" and="" aortic="" arterial="" associated="" at="" atherosclerosis="" attributed="" blood="" blunted="" by="" conclusion="" corrected="" did="" differ="" effects="" for="" function.="" groups.="" heart="" hunter-gather="" in="" is="" least="" lifestyle="" low="" lower="" not="" of="" on="" p="" partly="" pressures="" rate="" risk="" stiffness="" structure="" the="" to="" tp="" translated="" weight="" with="">