La dépression vous connaissez mais ce que vous ne savez peut être pas c'est que dans les dépressions légères ou modérées les antidépresseurs ne sont pas validés, ils n'ont pas fait la preuve de leur efficacité par rapport à un placebo... L'inflammation vous connaissez moins mais sachez que l'inflammation est impliquée dans tous les processus pathologiques graves, maladies athéromateuses, cancers, Alzheimer etc. La première cause de syndrome inflammatoire chronique est le tabac fumé. Les autres sont alimentaires.
Les aliments riches en oméga 6 sont :
les huiles de tournesol, sésame, maïs, soja, carthame
les animaux terrestres ou marins nourris avec ces aliments en particulier les tourteaux de tournesol soja, maïs
les produits laitiers de ces animaux
les céréales en général
Les aliments riches en oméga 3 sont:
les feuilles salades épinards choux etc
les animaux marins sauvages et leurs abats foie de morue ou de lotte
les animaux terrestres sauvages ou élevés à l'herbe
les produits laitiers de ces animaux
le lin le colza
les noix
Faites votre choix à l'achat au moment de remplir le caddie... Et retenez qu'il ne suffit pas de manger des aliments riches en oméga 3 ou des suppléments oméga 3 il faut diminuer les omégas 6!
Depressive Symptoms, omega-6:omega-3 Fatty Acids, and Inflammation in
Older Adults
JANICE K. KIECOLT-GLASER, PHD, MARTHA A. BELURY, PHD, KYLE PORTER, MAS, DAVID Q. BEVERSDORF, MD,
STANLEY LEMESHOW, PHD, AND RONALD GLASER, PHD
Objective: To address how interactions between polyunsaturated fatty acid (PUFA) levels and depressive symptoms were related
to proinflammatory cytokine synthesis. Depression and stress promote proinflammatory cytokine production. Dietary intakes of
omega-3 (n-3) and omega-6 (n-6) PUFAs also influence inflammation; high n-6:n-3 ratios enhance proinflammatory cytokine
production, although n-3 has anti-inflammatory properties. Methods: Blood samples from 43 older adults (mean age � 66.67 years, SD � 10.09) provided data on PUFAs and tumor necrosis factor (TNF)-�, interleukin (IL)-6, and IL-6 soluble receptor (sIL-6r).
Depressive symptoms were assessed by the Center for Epidemiological Studies Depression Scale. Results: Depressive symptoms
and n-6:n-3 ratios worked together to enhance proinflammatory cytokines beyond the contribution provided by either variable
alone, with substantial variance explained by their interaction: 13% for IL-6 and 31% for TNF-�, whereas full models accounted
for 18% and 40%, respectively. Although predicted cytokine levels were consistent across n-6:n-3 ratios with low depressive
symptoms, higher n-6:n-3 ratios were associated with progressively elevated TNF-� and IL-6 levels as depressive symptoms
increased. Higher levels of sIL-6r were associated with higher n-6:n-3 ratios. Six individuals who met the criteria for major
depressive disorder had higher n-6:n-3 ratios and TNF-�, IL-6, and sIL-6r levels than those who did not meet the criteria; excluding these six individuals reduced the variance explained by the depressive symptoms and n-6:n-3 ratio interaction. Conclusions: Diets with high n-6:n-3 PUFA ratios may enhance the risk for both depression and inflammatory diseases.
Key words: depression, proinflammatory cytokines, omega-3, psychoneuroimmunology.
Les aliments riches en oméga 6 sont :
les huiles de tournesol, sésame, maïs, soja, carthame
les animaux terrestres ou marins nourris avec ces aliments en particulier les tourteaux de tournesol soja, maïs
les produits laitiers de ces animaux
les céréales en général
Les aliments riches en oméga 3 sont:
les feuilles salades épinards choux etc
les animaux marins sauvages et leurs abats foie de morue ou de lotte
les animaux terrestres sauvages ou élevés à l'herbe
les produits laitiers de ces animaux
le lin le colza
les noix
Faites votre choix à l'achat au moment de remplir le caddie... Et retenez qu'il ne suffit pas de manger des aliments riches en oméga 3 ou des suppléments oméga 3 il faut diminuer les omégas 6!
Depressive Symptoms, omega-6:omega-3 Fatty Acids, and Inflammation in
Older Adults
JANICE K. KIECOLT-GLASER, PHD, MARTHA A. BELURY, PHD, KYLE PORTER, MAS, DAVID Q. BEVERSDORF, MD,
STANLEY LEMESHOW, PHD, AND RONALD GLASER, PHD
Objective: To address how interactions between polyunsaturated fatty acid (PUFA) levels and depressive symptoms were related
to proinflammatory cytokine synthesis. Depression and stress promote proinflammatory cytokine production. Dietary intakes of
omega-3 (n-3) and omega-6 (n-6) PUFAs also influence inflammation; high n-6:n-3 ratios enhance proinflammatory cytokine
production, although n-3 has anti-inflammatory properties. Methods: Blood samples from 43 older adults (mean age � 66.67 years, SD � 10.09) provided data on PUFAs and tumor necrosis factor (TNF)-�, interleukin (IL)-6, and IL-6 soluble receptor (sIL-6r).
Depressive symptoms were assessed by the Center for Epidemiological Studies Depression Scale. Results: Depressive symptoms
and n-6:n-3 ratios worked together to enhance proinflammatory cytokines beyond the contribution provided by either variable
alone, with substantial variance explained by their interaction: 13% for IL-6 and 31% for TNF-�, whereas full models accounted
for 18% and 40%, respectively. Although predicted cytokine levels were consistent across n-6:n-3 ratios with low depressive
symptoms, higher n-6:n-3 ratios were associated with progressively elevated TNF-� and IL-6 levels as depressive symptoms
increased. Higher levels of sIL-6r were associated with higher n-6:n-3 ratios. Six individuals who met the criteria for major
depressive disorder had higher n-6:n-3 ratios and TNF-�, IL-6, and sIL-6r levels than those who did not meet the criteria; excluding these six individuals reduced the variance explained by the depressive symptoms and n-6:n-3 ratio interaction. Conclusions: Diets with high n-6:n-3 PUFA ratios may enhance the risk for both depression and inflammatory diseases.
Key words: depression, proinflammatory cytokines, omega-3, psychoneuroimmunology.
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