Statins seem to kill the benefit of exercise

Figure 1. 

Cardiorespiratory Fitness

(A) Peak oxygen consumption (Vo₂peak) before (Pre) and after (Post) 12 weeks of supervised aerobic exercise training (Ex) or combination exercise-plus-statin therapy (St+Ex). (B) Vo₂peak presented as within-group change (Δ) from baseline. Data are expressed as mean ± SE. ^∗p < 0.005 for within-group change from baseline. §p < 0.005 for between-group difference in change from baseline.

Figure 2. 

Citrate Synthase Activity, a Marker of Skeletal Muscle Mitochondrial Content

(A) Citrate synthase activity before and after 12 weeks of supervised aerobic exercise training or combination exercise-plus-statin therapy. (B) Citrate synthase activity presented as within-group change from baseline. Data are expressed as mean ± SE. ^∗p < 0.05 for within-group change from baseline. §p < 0.05 for between-group difference in change from baseline. Abbreviations as in Figure 1.

http://www.sciencedirect.com/science/article/pii/S0735109713014034

http://www.sciencedirect.com/science/article/pii/S0735109713014022