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vendredi 19 septembre 2014

Statins seem to kill the benefit of exercise

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Figure 1. 
Cardiorespiratory Fitness
(A) Peak oxygen consumption (Vo2peak) before (Pre) and after (Post) 12 weeks of supervised aerobic exercise training (Ex) or combination exercise-plus-statin therapy (St+Ex). (B) Vo2peak presented as within-group change (Δ) from baseline. Data are expressed as mean ± SE. p < 0.005 for within-group change from baseline. §p < 0.005 for between-group difference in change from baseline.




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Figure 2. 
Citrate Synthase Activity, a Marker of Skeletal Muscle Mitochondrial Content
(A) Citrate synthase activity before and after 12 weeks of supervised aerobic exercise training or combination exercise-plus-statin therapy. (B) Citrate synthase activity presented as within-group change from baseline. Data are expressed as mean ± SE. p < 0.05 for within-group change from baseline. §p < 0.05 for between-group difference in change from baseline. Abbreviations as in Figure 1.



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