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mardi 30 juillet 2013

You need information you don't need a guru!

So keep reading Dysnutrition!
Disruption of the old system of agribusiness, products instead of food and obesogens (1) will occur  spontaneously with the growing power of scientific research, information and open data on health care systems.



Dysnutrition is the main-way to diseases of affluence. But it is in tandem with sedentary lifestyle!

Paleo broth

Leaves of Romaine salad, celeri, germinated chia seeds, white onions, bones and bone marrow from grassfed veal, purslane, tomatoes, basil, unfiltered olive oil, a touch of Curcuma and Guérande salt.
Slow cooking mandatory...
One of the greatest mistake we do in Summer is to decrease fat intake...

Keep your kitchen safe: be careful with pollutants and not only with microorganisms!

+ 3,75 IQ score at 7 years old: how to do it?

Breastfeeding, so simple.

You have type 2 diabetes? You treat D2? URGENT: read these papers


mercredi 24 juillet 2013

Do you need to forage if you swich to paleo diet?

"« Il m'a fallu du temps avant d'oser proposer une approche plus tranchée, plus radicale. Faire une cuisine 100 % chilienne, pensée comme un état des lieux de notre habitat sauvage. Pour célébrer produits et méthodes des tribus des Mapuches, natifs du centre-sud du Chili... Au départ, quand le restaurant a été créé, on nous a pris pour des fous. »"

You can add several other foods to this list of junk food!

About Fructose

Paleo videos

Bowel cancer and diet: sugar and carbs another time implicated?

Supplements? Another piece!

The debate about supplements is very complex:
1/ supplements are like drugs they need evidence, clinical trials, personalized data
2/ supplements must be evaluated in the setting of extended life expectancy
3/ supplements tend to change human behavior and usually decreases the seek for healthy diet!

jeudi 18 juillet 2013

As we experience in our life: High GI foods are addictive...

It is like tobacco and lung cancer...

All the partners of the agro-food industry will negate it even after it is proven by fMRI studies!

Effects of dietary glycemic index on brain regions related to reward and craving in men1,2,3,4

  1. David S Ludwig
-Author Affiliations
  1. 1From the New Balance Foundation Obesity Prevention Center, Boston Children's Hospital, Boston, MA (BSL, CBE, and DSL); Ulm University, Ulm, Germany (BSL); the Beth Israel Deaconess Medical Center, Boston, MA (DCA and RR); Brigham and Women's Hospital, Boston, MA (LMH, ES, and JMG), and Harvard Medical School, Boston, MA (BSL, DCA, LMH, ES, RR, CBE, JMG, and DSL).
-Author Notes
  • 2 Funding organizations had no role in the design or conduct of the study; collection, analysis, or interpretation of data; or preparation, review, or approval of the manuscript. The content of this manuscript is solely the responsibility of the authors and does not necessarily represent the official views of the National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Mental Health, National Center for Research Resources, NIH, or Harvard Catalyst.
  • 3 Supported by grant K24DK082730 from the National Institute of Diabetes and Digestive and Kidney Diseases (Bethesda, MD), grant R01MH80729 from the National Institute of Mental Health (Bethesda, MD), and grant UL1 RR025758-01 from the National Center for Research Resources (Bethesda, MA) to the Harvard Catalyst Clinical and Translational Science Center at Harvard University; by a grant from the Pediatric Endocrine Society (McLean, VA), a grant from the Endocrine Fellows Foundation (Washington, DC); and by a grant from the New Balance Foundation (Boston, MA).
  • 4 Address correspondence to DS Ludwig, Division of Endocrinology, Boston Children's Hospital, 300 Longwood Avenue, Boston, MA 02115. E-mail:

lundi 15 juillet 2013

Insulin: one important physiological point!

Insulin stops the use of fat as an energy source by inhibiting the release of glucagon.

So what do you do metabolically when you exercise and drink sugar sweetened beverages?

You stop the use of fat!

So if you want to use fat reduce drastically sugars and keep good fats in your diet!

A propos de l'article de Susan Swithers au sujet des édulcorants

 Je lis le papier de S Swithers. Je vous donne le lien... 
Les conclusions de cette revue générale (ce n''est pas une méta analyse) développée à l'appui d'une thèse: les effets métaboliques perturbateurs des édulcorants ne sont pas aussi définitifs que ne le signale la presse. 

1/ les boissons sucrées produisent des effets doubles: métaboliques et neurobiologiques (sur le cerveau). Elles sont clairement impliquées en terme de causalité dans l'épidémie d'obésité. Les individus en surpoids doivent les éviter s'ils veulent reprendre le controle de leur poids. 

2/ les boissons aux édulcorants et les édulcorants produisent des effets neurobiologiques (sur le cerveau). Il est possible que ces effets conduisent à des comportemenst "contrintuitifs" chez certains et d'éviction des produits sucrés chez d'autres (nous sommes tous différents...). Les articles référencés sont très difficiles à anaklyser et S Swithers le souligne car certains parlent de l'Imc, d'autres des maladies cardiovasculaires en général d'autres d'HTA... .

C'est pourquoi nous ne pouvons que constater que nous savons assez peu de choses en réalité sur les édulcorants puisque les études interventionnelles sont au nombre de ...2! Comment aider ceux qui voudraient en consommer? 

1. Il faut éviter les boissons sucrées et ce dès la plus petite enfance. 
2. pour ceux qui ne sont pas en surpoids à l'âge adulte remplacer le sucre par des édulcorants produit INDUBITABLEMENT des effets métaboliques favorables. Si le controle du poids est aisé (il faut pour cela une simple balance et un carnet...) il n'y a pas lieu de les supprimer. 
3. Les édulcorants ne sont pas égaux... Il serait trop long de développer ici... 
4.Les effets neurobiologiques sont très mal connus. Comment les compensations se font elles entre la récompense, le plaisir et l'addiction? 
5. Quelles sont les csq des édulcorants sur la flore? 
6. Les édulcorants sont attaqués par le lobby sucrier et vice versa si bien qu'il est difficile d'y voir clair actuellement. 

En conclusion le message à retenir est: 

diminuez vos apports en sucres, qu'ils soient sucrés ou non (les amidons des pates pains riz pollenta etc...). Je conseille de diminuer pas de substituer!.

Addiction or reward? Not an easy question!

Dietary Addictions: Why eating healthfully is so difficult

Written by Alan Goldhamer, D.C.   
Wednesday, 21 May 2008 12:31
Today, most people acknowledge that drugs, including nicotine, alcohol, caffeine and cocaine, are addictive. It is common knowledge that repeated exposure to these substances can result in physical addiction and that the consequences of addiction can be devastating. Escaping the pleasure trap of addiction can be extremely difficult. Even the most effective treatment programs fail miserably for the vast majority of addicts. For example, the most effective treatment programs for alcoholism involve a period of intensive in-patient care for 30 days, followed by outpatient support often involving 90 visits in 90 days to a 12-step program. Of the highly motivated addicts who complete the program, over 70 percent fail.
Unlike drugs, whose use is voluntary, food is essential for life. Some foods, particularly highly processed, stimulating foods, elicit responses similar to addiction. Not all individuals respond to the addictive nature of highly processed foods, and those who do may not respond in exactly the same way.
The dietary pleasure trap is often hidden and extremely difficult to escape. The most common result is obesity. The medical management of obesity has a lower cure rate than the treatment of most cancers and recidivism exceeds 90 percent in most studies.
The key to understanding food addiction is to understand the nature of highly processed foods. Natural foods contain carbohydrates, protein and fat, but they also contain fiber and water. When foods are highly processed, the fiber and water is often removed or modified, as in the case of flour, where the grain is ground into a very fine powder. This process makes the carbohydrate in the grain infinitely more available to the body. Another technique in processing food is to isolate and concentrate one component of food as is done in the production of oil or sugar. When the desired component is separated from the naturally occurring fiber, water, and other nutrients, it is much easier to overeat. This effect is further enhanced because the artificially concentrated taste of the isolated substance is very stimulating to the taste buds.
When human beings (or other animals) eat highly concentrated processed foods, including oil, sugar and flour products, they artificially stimulate dopamine secretion in the brain. Dopamine is the neurochemical most closely associated with pleasure. The more highly concentrated the food (calories per pound), the more dopamine is secreted by the brain, the better the food “tastes” and the more effective the pleasure trap is. In addition, artificially concentrated foods are devoid of the whole food factors, including fiber, that trigger the satiety mechanisms in the brain that are responsible for the feeling of fullness and the regulation of total calorie intake. When satiation is not triggered normally, overeating becomes inevitable and obesity eventually follows. When they say, “betcha can’t just eat one,” they’re not kidding!
Over two-thirds of adults in the United States are now overweight or obese. The epidemic of obesity in industrialized society is the result of the dietary pleasure trap and the overeating that it encourages.
One reason it is so difficult for people to escape the dietary pleasure trap is the belief in the concept of moderation. A common belief is that everything in moderation is healthful. Although there are some people who can eat processed foods in moderation, if you are struggling with your weight, chances are YOU are not one of them. When it comes to addiction, moderation is NOT the answer.
We do not advise alcoholics to “drink moderately.” We do not advise alcoholics to put their alcohol in a smaller cup to reduce their over consumption, nor do we advise them to put their drink down between sips. We don’t suggest drinking just beer and wine and we don’t tell them to count their ounces of intake. Above all else, most addicts dearly hold to the belief that they can continue to drink moderately, but experience will soon prove this to be a fallacy. We do not advise alcoholics to drink moderately because it DOES NOT WORK!
Fat people caught in the dietary pleasure trap are told that they just need some discipline, or they need to chew their food more, put their fork down between each bite, etc. They are told to eat in moderation. This strategy will fail miserably for dietary addicts in the same way it fails for drug addicts.
The 100 percent effective system for treating alcoholism involves the elimination of alcohol. The 100 percent effective system for treating dietary addiction and the resulting obesity involves the elimination of the highly processed foods that can fool the satiety systems of the brain and result in the artificial stimulation of the pleasure inducing neurochemical dopamine.
The most effective way to lose weight and regain health is to adopt a health promoting diet derived from abundant quantities of fresh fruits and vegetables, and the variable addition of raw nuts and seeds, minimally processed starchy vegetables, (including potatoes, yams, squashes, etc.), whole grains (brown rice, millet, quinoa, but NOT flour products), and beans (such as lentils, peas, etc.). The elimination or severe limitation of all animal products is also recommended for health reasons not necessarily related to the pleasure trap.
This type of health promoting diet, in conjunction with appropriate sleep and exercise, will result in the normalization of weight. Most overweight people who adopt this eating plan will lose 1-2 pounds a week.
Those individuals following a strictly vegan diet should insure a reliable source of vitamin B12 and adequate exposure to sunshine to insure production of vitamin D.
Just as some alcoholics find that “just quit drinking” is not always easy, many overweight people struggle establishing a health promoting diet. Addicts of all kinds often find benefit in taking a “time out” in a health promoting environment that avoids the distractions and temptations associated with modern life. In addition to a health promoting environment, a period of medically supervised water-only fasting can also prove to be an effective adjunct. Fasting can clear the palate and help to “reset” the appestatic mechanisms (similar to rebooting your computer). Many find fasting to be most effective AFTER a prolonged period of dietary compliance. The longer you sustain dietary excellence PRIOR to fasting, the more effective fasting tends to be in promoting a return to optimum health.

Don't miss the sun exposure!

UVA lowers blood pressure and vasodilates the systemic arterial vasculature by mobilisation
of cutaneous nitric oxide stores
D Liu,1 BO Fernandez,3 NN Lang,2 JM Gallagher,4 DE Newby,2 M Feelisch3 and RB Weller1,5 1
Dermatology, University of Edinburgh, Edinburgh, United Kingdom, 2 Cardiology, University
of Edinburgh, Edinburgh, United Kingdom, 3 Medicine, University of Southampton,
Southampton, United Kingdom, 4 Leithmount Surgery, Edinburgh, United Kingdom and 5
Centre for Inflammation Research, University of Edinburgh, Edinburgh, United Kingdom
The incidence of hypertension and cardiovascular disease (CVD) correlates with latitude and rises
in winter. Population vitamin D levels inversely correlate with CVD, but oral supplementation does
not alter CVD rates. Skin contains large stores of nitrite(NO2) and nitrate(NO3). Nitrate is biologically
inert, but can be photo-reduced to active NO2 and nitric oxide (NO). The dermal vasculature
enables rapid systemic dispersal of NO2 and NO.We hypothesised that ultraviolet A (UVA) mobilises
NO bioactivity from skin to circulation to exert beneficial cardiovascular effects. Vit’ D is a marker
for sunlight exposure. 24 healthy volunteers were sham (temp’ control) irradiated then actively irradiated
with 20 J/cm2 UVA. Mean arterial pressure (MAP) fell and heart rate rose during active but
not sham irrad’n (3.50°”0.73 mmHg vs 2.80°”0.98). The MAP fall was sustained for 50 mins in the
active group only. Temperature rise was the same in both groups. Circulatory nitrite rose (0.50°”0.04
μM to 0.72°”0.04 μM p<0 .001="" 0.64="" 8.99="" and="" during="" fell="" font="" nitrate="" p="" to="">
active, but not sham irradiation. There was no change in circulating vitamin D levels. 12 volunteers
had forearm blood flow (FBF) measured by venous plethysmography while 8 μmol/min of
the NOS antagonist L-NMMA was infused to the brachial artery. FBF rose during active but not sham
irradiation (23.7°”6.5 % over baseline vs no change p<.0002). Physiological levels of UVA irradiation
cause systemic vasodilation and lower BP in a vitamin D and NOS independent manner. Deaths
from CVD and stroke are 60 to 100 times higher than from skin cancers in northern Europe. This
study provides a mechanistic explanation for the inverse correlation between sunlight exposure
and CVD mortality. Sunlight has beneficial effects independently of vitamin D synthesis.

mercredi 3 juillet 2013

Urgent: breast cancer and diet/ Urgent: cancer du sein et alimentation

What is already known on this topic

Breast cancer is one of the most common cancers and the leading cause of cancer death among women in the world
Epidemiological studies suggest that fish and n-3 polyunsaturated fatty acids intake have a protective role in breast cancer, though
results from prospective studies are inconsistent

What this study adds

High intake of marine n-3 polyunsaturated fatty acids is associated with 14% reduction in risk of breast cancer
Each 0.1 g/day or 0.1% energy/day increment of intake was associated with a 5% reduction in risk

lundi 1 juillet 2013

L'article le plus médiocre sur le régime paléo!

Si, si nous mangeons ensemble! Et grâce a cette diversité des comportements alimentaires nous apprenons les uns des autres nous comprenons mieux et nous échangeons!