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vendredi 26 juin 2015

Med diet and CVD

Antibiotics in herds no longer used for growth are now used prophylactically...

"Antibiotics should be used to treat existing infections. Individual treatment should always be the norm and herd treatment the exception."

"In France 60% of rural veterinarians’ total turnover comes from antibiotics sales. Self-regulation is not compatible with the responsible use of antibiotics, especially as pharmaceutical laboratories can grant discounts depending on the quantity ordered ."
Antibiotiques, Menace sur notre santé, UFC Que-Choisir, March 2014

Eventually cattle are treated like humans. The former because of growth potential of antibiotics the second because of "free" medicine and consuming habits.

Big Sugar needs Big Government

jeudi 25 juin 2015

How much protein a day? You have to check your status

Nitrogen balance

For french speaking people:


  • Prélèvement de sang veineux, au pli du coude en général. Le tube de prélèvement peut éventuellement contenir un anticoagulant.
  • Pas de conditions particulières.


Recueil des urines de 24 heures dans un récipient permettant une mesure facile du volume émis (diurèse). Il est souvent associé à un dosage de l'urée dans le sang.

Valeurs normales de l'urée dans le sang

  • Homme : 3 à 8,33 mmol/l soit 0.18 à 0.50 g/l
  • Femme : 2.5 à 8.33 mmol/l soit 0.15 à 0.50 g/l

Valeurs normales de l'urée dans les urines

  • Nouveau-né et nourrisson : 2,5 à 66 mmol/24 h soit 0,15 à 4 g/24 h
  • Enfant jusqu'à 15 ans : 66 à 330 mmol/24 h  soit 4 à 20 g/24 h
  • Adulte : 250 - 580 mmol / 24 h   soit 15 - 35 g / 24 h

Variations physiologiques de l'urée

  • Âge : nourrisson connaissent une baisse de -30% ; adultes>55ans, une hausse de +20 %
  • Sexe : homme/femme +5%
  • Grossesse : baisse ente 30 et 60%
  • Régime hyperprotidique : hausse entre 50 et 80%
  • Jeûne prolongé : forte baisse

What Lipoproteins particles in the human blood look like?

(a) VLDL particles, (b) chylomicrons, (c) LDL particles, and (d) HDL particles. The dark bar at the bottom of each shot is 1000 A in length, or 100 nm (A = angstrom; nm = nanometer; 1 nm = 10 A)

mardi 23 juin 2015

From Cell Metabolism paper to your plate: near fasting protocol on 5 days

Those who read this blog will not be surprised...

If you want to regenerate you have to induce a metabolic stress which mimics our evolutionary past.
Get the protein first or the big salad first but after the two you will be full...
Greens, raw that means salads, with tomatoes, onions, basil, cucumber and red pepper.
Then a steak like bavette (flank steak) or onglet (hanger steak) raw or rare with grain mustard.
At dinner bone broth, soup with mushrooms and fat, lot of fats not refined, not heated, not transformed.
Olive and avocados instead of refined olive oil...
Almonds and other nuts.
Fat meat from lamb, bone marrow, fatty fishes.
According to your metabolism and genomics I advise you to eat some tubers if you do any sport and seasonal raw fruit.
What about dairy?
No lactose so either butter raw from grass fed cattle or completely fermented cheeses. Another time you have to test your results with this amount of dairy.

The way they advocate to do near fasting is interesting especially for people who would not to stop exercise.

And this TED conference

Trans fats and all cause mortality

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Paleodiet is not meat diet

Trans fats and memory

mercredi 17 juin 2015

God delusion


Vitamin D and Crohn's disease

Les Grands Buffets à Narbonne

You can eat paleo every day...

Unnecessary antibiotics could have long term side effects

Figure thumbnail fx1


Acquisition of the intestinal microbiota begins at birth, and a stable microbial community develops from a succession of key organisms. Disruption of the microbiota during maturation by low-dose antibiotic exposure can alter host metabolism and adiposity. We now show that low-dose penicillin (LDP), delivered from birth, induces metabolic alterations and affects ileal expression of genes involved in immunity. LDP that is limited to early life transiently perturbs the microbiota, which is sufficient to induce sustained effects on body composition, indicating that microbiota interactions in infancy may be critical determinants of long-term host metabolic effects. In addition, LDP enhances the effect of high-fat diet induced obesity. The growth promotion phenotype is transferrable to germ-free hosts by LDP-selected microbiota, showing that the altered microbiota, not antibiotics per se, play a causal role. These studies characterize important variables in early-life microbe-host metabolic interaction and identify several taxa consistently linked with metabolic alterations.

mardi 16 juin 2015

Nutella et Ségolène Royal: les poncifs perdurent

Dieting works but not with full processed food regime

What is the seven countries study?

Dots are cohort studies inside the seven countries

Sat fats, trans fats, roasted coffee and bullet roasted coffee

Just Make it once!

samedi 13 juin 2015

Veganism is a choice not a way evolution took to enlarge our brain

Is nutritional epidemiology fake science?

An example of the lack of science in nutritional epidemiological data

Most dietary data is based on people recalling what they ate. This has allowed for dietary guidelines to be formed, but there's a small problem: the data could be wildly inaccurate, and dietary guidelines completely wrong.

Don't worry about dietary cholesterol (1)

Side effects of guidelines

More on LCHF diets

The stupidity of state regulation about sugar

High casein diet

jeudi 11 juin 2015

Adaptation about phytate and iron

Paleodiet and monkey diet

In the light of evolution: human brain

Paradigm shift is painful

Probiotics do not decrease weight

Lactose tolerance in the Bronze age

Carbohydrates tolerance

mercredi 10 juin 2015

Chenin Blanc Afrique du Sud

Understanding the NNT

Obesity research

We are not what we eat except for essential nutrients!
For the others we are what our body and especially our liver transform from our diet.
So what we eat matter because every nutrient sends a signal to our body and deeply to our genomics.

Interesting effort to make sense with epidemiological correlations

Take the quizz

mardi 9 juin 2015

The failure of label regulation

How a diabetic patient could avoid this highly sugar loaded biscuit?

No nutritional information but a warning on allergens!

This biscuit is given to passengers on Air France domestic flights.

samedi 6 juin 2015

Some explanations about fat and sugar

Vit B12 in vegans

Are insulin or igf levels a market of response of cancer to keto diet ?

Transit and constipation

The prescription of daily activity

Proportion of weekly waking hours spent in activity modes, ranging from time spent sitting through to vigorous physical activity (adapted from Townsend et al).18,66 Values R, 1, 2, 3 and 4 represent behavioural “gears” synonymous to a car, where R = “reverse”, 1 and 2 = light activities within daily living, 3 and 4 are moderate to vigorous activities either in daily life or as part of leisure-time pursuits, exercise and sport. Many health promotion and physical activity interventions aim to change people's behaviour by attempting to go from R to 3rd gear, missing targeted interventions in 1st and 2nd gear and thus resulting in behavioural “stalling” (relapse), as would occur in a car if one attempted to go from Reverse into 3rd or 4th gear. Avoiding sedentary behaviour at work fulfils engaging people in activity at gears 1 and 2.

vendredi 5 juin 2015

The need for unbiased advice about children food in french schools

the job of the school is the health of children not the compliance with religious bans or choices.

Parents sugared their children to obesity

Carbobesity: central storage

Fat vs Skinny Man

Central obesity means that fat is stored in your abdomen around the organs.

Fiber and the tricky count of carbs on labels


This one is a little confusing. Fiber, specifically soluble fiber, reduces the bile that is reabsorbed in the GI tract. Bile is a substance produced by the liver and excreted by the gallbladder that helps us absorb dietary fats. Bile is made in the liver using cholesterol. It is stored in the gallbladder and released when there is fat in the GI tract to be absorbed. Dietary fiber prevents the re-absorption of bile in the GI tract (we can re-use bile so we don’t have to keep making it), causing it to be excreted in our fecal matter. The liver is forced to use the cholesterol in our blood to produce more bile, thus decreasing our overall blood cholesterol.

Sugar everywhere, accomplice regulators