mardi 23 avril 2019

Discrepancies in absolute risks among studies

Statins in primary prevention: a cohort study
https://heart.bmj.com/content/early/2019/04/16/heartjnl-2018-314253
2260 vs 1970 per 100000 both under statins but the second group has "optimal" LDLc reduction
12142 events in 84609 patients during 6,2 y
10656 in 80802 patients during 6,2 y
Absolute risk: 13,19% versus 14,86%


Olive oil vs (olive oil + nuts) vs standard low fat: RCT
https://www.nejm.org/doi/full/10.1056/NEJMoa1800389
96 versus 83 versus 109
respectively 2543, 2454, 2450 during 4,8y
96/2543= 3,78%
83/2454= 3,38%
109/2450=4,45%



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