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mercredi 29 février 2012

Chronobiology and diet

Short timesleepers, rs1801260 CLOCK variant of the Clock gene, and other factors may interfere with obesity and the Metabolic syndrome.


http://www.medscape.com/viewarticle/721923_8
721923-fig2.jpg
Rhythmic expression of clock genes (hPer2hBmal1 and hCry1) in human subcutaneous and visceral adipose tissue(A) hPer2(B) hBmal1 and (C) hCry1. Adipose depots were isolated at 6-h intervals over the course of the day from adipose tissue cultures (time at 0, 6, 12 and 18 h). Results are presented relative to the lowest basal relative expression for each gene.
Data are reported as means ± standard error of the mean (SEM). SEM of differences in cycle threshold are represented in parenthesis.
AU: Arbitrary unit.
Aschoff J: Circadian rhythms: general features and endocrinological aspects. In: Endocrine Rhythms. Krieger DT (Ed.). Raven Press, NY, USA, 1–61 (1979).



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