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samedi 28 mars 2015

How changes in food availability affect subsequent generations

http://www.biomedcentral.com/1471-2156/15/12

For CVD it's change in food availability and consumption in your PATERNAL grand mother which modify your risk profile.

Table 2

Grandparents' childhood experience of drastic change in food availability, from one year to the next year, going from poor to good and good to poor by descendants' cardiovascular mortality*
Poor to goodPoor to goodGood to poorGood to poor
MenWomenMenWomen
Paternal grandfather0.90 (0.45-1.80)1.42 (0.64-3.14)1.08 (0.29-4.00)0.15 (0.02-1.41)
Patermal grandmother0.54 (0.24-1.20)1.62 (0.58-4.52)0.86 (0.22-3.3)21.27 (2.24-202.47)
Maternal grandfather1.17 (0.58-2.35)1.22 (0.46-3.23)1.28 (0.31-5.34)3.37 (0.59-19.22)
Maternal Grandmother0.60 (0.24-1.49)0.91 (0.30-2.75)0.75 (0.22-2.58)0.16 (0.02-1.32)
Index cases151151126126
*Associations are presented as Hazards ratios (HRs) with 95% confidence intervals (CIs 95%). The models are adjusted for birth cohort, mother´s literacy, father´s death before the index person attained 13 years of age. Bold numbers indicate significant associations, p<0 .05.="" p="">
Bygren et al.
Bygren et al. BMC Genetics 2014 15:12   doi:10.1186/1471-2156-15-12

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