The debate about usefulness of supplements in prevention of cardiovascular and other chronic non communicative diseases is beginning again when industry markets a new nutraceutical product.
I believe that the level of proof is the same as fr drugs. Clinical results on deaths and major cardiovascular events. I mean stroke, MI and lower limb ischemia.
All improvements in the so called lipid profile are useless because they do not translate in life extension or less major ischemic events.