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lundi 10 août 2015

IMPROVE-IT: data on patient lipid profiles

LDL-C (mg/dL)
 n51561284317999
 Median (IQR)100 (85-113)93 (77-108)95 (79-110)
HDL-C (mg/dL)
 n51421271717859
 Median (IQR)40 (33-49)40 (33-49)40 (33-49)
Triglycerides (mg/dL)
 n51421276217904
 Median (IQR)114 (79-165)124 (88-175)120 (85-172)
Creatinine (mg/dL)
 n51591287218031
 Median (IQR)1.0 (0.8-1.2)1.0 (0.8-1.2)1.0 (0.8-1.2)
Creatinine clearance (mL/min)
 n51361283617972
 Median (IQR)87 (69-110)83 (64-105)84 (65-106)
Abbreviation: IQR, interquartile range.

These data were at the inclusion of patients. It is striking that patients in the ACS group has a LDL level of 100 mg/dl! It is hard to believe that LDL causes heart attacks isn't it?

Distribution of particles and TG levels in fasting plasma are the following
Figure 3. 
Distribution of LDL-C A, HDL-C B, and triglycerides C at entry. Q1,Q3, first and third quartiles.

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