http://www.nature.com/nature/journal/vaop/ncurrent/full/nature15726.html
5. Too much – from supplements – can be harmful
All those benefits are seen with foods containing beta-carotene, not beta-carotene supplements. In fact, research suggests that smokers who take high amounts of beta-carotene supplements are at increased risk of lung cancer. (Population studies link foods rich in carotenoids with lower risk of lung cancer.) For cancer prevention, AICR recommends not to rely on supplements.
http://www.aicr.org/enews/2015/11-november/7-Things-You-Should-Know-About-Whats-Making-Your-Squash-Orange.html
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